Peter Traxler

Pooled CRISPR screening with single-cell transcriptome readout

Paul Datlinger, André F. Rendeiro, Christian Schmidl et al. · Nature Methods · 2017 · 1.1K citations · Full text

Off-target Effect, Genetics, Single-cell Genomics +7

Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma.

Christiane J. Bruns, Carmen C. Solórzano, Matthew T. Harbison et al. · PubMed · 2000 · 501 citations

Endothelial Cells, Chemoprevention Strategy, Pathology +16

Imatinib Mesylate Is a Potent Inhibitor of the ABCG2 (BCRP) Transporter and Reverses Resistance to Topotecan and SN-38 <b> <i>in Vitro</i> </b>

Peter J. Houghton, Glen S. Germain, Franklin C. Harwood et al. · Cancer Research · 2004 · 319 citations · Full text

AEE788

Peter Traxler, Peter R. Allegrini, Ralf Brandt et al. · Cancer Research · 2004 · 317 citations

Angiogenesis, Family Members, Medicine +10

Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition

Ranjit K. Goudar, Qing Shi, Mark D. Hjelmeland et al. · Molecular Cancer Therapeutics · 2005 · 244 citations · Full text

Neuro-oncology, Mammalian Target, Glioma +13