Christiane J. Bruns

Distinct Populations of Cancer Stem Cells Determine Tumor Growth and Metastatic Activity in Human Pancreatic Cancer

Patrick Hermann, Stephan Huber, Tanja Herrler et al. · Cell stem cell · 2007 · 2.9K citations · Full text

Medicine, Cancer Biology, Oncology +16

Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor

Markus Guba, Philipp von Breitenbuch, Markus Steinbauer et al. · Nature Medicine · 2002 · 1.7K citations

Medicine, Oncology, Pharmacology +16

Efficacy of stapler versus hand-sewn closure after distal pancreatectomy (DISPACT): a randomised, controlled multicentre trial

Markus K. Diener, Christoph M. Seiler, Inga Rossion et al. · The Lancet · 2011 · 553 citations

Medicine, Perioperative Medicine, Surgery +14

Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma.

Christiane J. Bruns, Carmen C. Solórzano, Matthew T. Harbison et al. · PubMed · 2000 · 501 citations

Medicine, Oncology, Pharmacology +17

Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms.

Christiane J. Bruns, Matthew T. Harbison, Darren W. Davis et al. · PubMed · 2000 · 422 citations

Medicine, Oncology, Pharmacology +17