Concepedia

Author

Franklin C. Harwood

St. Jude Children's Research Hospital

Also Known As

F C Harwood, Franklin C Harwood, Franklin C. Harwood

18

Publications

1.7K

Citations

16

H-Index

33

Concepts

All Affiliations

St. Jude Children's Research HospitalThe University of Tokyo
FC

About

Franklin C. Harwood is an author at St. Jude Children's Research Hospital specializing in medicine, pharmacology, and cell biology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

7

7

750

2

Cell Biology

4

4

601

3

Health Sciences

2

2

127

4

Biochemistry

2

2

307

5

Natural Sciences

1

1

75

Franklin C. Harwood

×

17

Publications

1.7K

Citations

16

H-Index

YearCitations

Imatinib Mesylate Is a Potent Inhibitor of the ABCG2 (BCRP) Transporter and Reverses Resistance to Topotecan and SN-38 <b> <i>in Vitro</i> </b>

Peter J. Houghton, Glen S. Germain, Franklin C. Harwood,

Cancer Research

2004

319

Biochemical correlates of mTOR inhibition by the rapamycin ester CCI-779 and tumor growth inhibition.

Lorina Dudkin, Michael B. Dilling, Pamela J. Cheshire,

PubMed

2001

232

Sustained Activation of the JNK Cascade and Rapamycin-Induced Apoptosis Are Suppressed by p53/p21Cip1

Shile Huang, Lili Shu, Michael B. Dilling,

Molecular Cell

2003

220

Gefitinib Enhances the Antitumor Activity and Oral Bioavailability of Irinotecan in Mice

Clinton F. Stewart, Markos Leggas, John D. Schuetz,

Cancer Research

2004

199

ETV7 is an essential component of a rapamycin-insensitive mTOR complex in cancer

Franklin C. Harwood, Ramon I. Klein Geltink, Brendan P. O’Hara,

Science Advances

2018

130

Inhibition of Mammalian Target of Rapamycin Activates Apoptosis Signal-regulating Kinase 1 Signaling by Suppressing Protein Phosphatase 5 Activity

Shile Huang, Lili Shu, John Easton,

Journal of Biological Chemistry

2004

109

A phase I clinical trial of 2-chlorodeoxyadenosine in pediatric patients with acute leukemia.

Victor M. Santana, J Mirro, Franklin C. Harwood,

Journal of Clinical Oncology

1991

96

4E-binding Proteins, the Suppressors of Eukaryotic Initiation Factor 4E, Are Down-regulated in Cells with Acquired or Intrinsic Resistance to Rapamycin

Michael B. Dilling, Glen S. Germain, Lorina Dudkin,

Journal of Biological Chemistry

2002

96

Biochemical pharmacology of 2-chlorodeoxyadenosine in malignant human hematopoietic cell lines and therapeutic effects of 2-bromodeoxyadenosine in drug combinations in mice.

Thomas L. Avery, Jerold E. Rehg, W C Lumm,

PubMed

1989

75

Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.

Kuntebommanahalli N. Thimmaiah, John Easton, Shile Huang,

PubMed

2003

74

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