Clinton F. Stewart

Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial

Amar Gajjar, Murali Chintagumpala, David M. Ashley et al. · The Lancet Oncology · 2006 · 935 citations

Neuro-oncology, Risk-adapted Craniospinal Radiotherapy, Oncology +5

Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1+/−p53−/− mice

Justyna T. Romer, Hiromichi Kimura, Susan Magdaleno et al. · Cancer Cell · 2004 · 520 citations · Full text

Oncogenic Agent, Medicine, Cell Death +10

Selumetinib in paediatric patients with BRAF-aberrant or neurofibromatosis type 1-associated recurrent, refractory, or progressive low-grade glioma: a multicentre, phase 2 trial

Jason Fangusaro, Arzu Onar‐Thomas, Tina Young Poussaint et al. · The Lancet Oncology · 2019 · 472 citations · Full text

Neuro-oncology, Tumoral Pathology, Pediatric Brain Tumors +12

Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog–Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032

Giles Robinson, Brent A. Orr, Gang Wu et al. · Journal of Clinical Oncology · 2015 · 448 citations · Full text

Bevacizumab-Induced Transient Remodeling of the Vasculature in Neuroblastoma Xenografts Results in Improved Delivery and Efficacy of Systemically Administered Chemotherapy

Paxton V. Dickson, John B. Hamner, Thomas L. Sims et al. · Clinical Cancer Research · 2007 · 436 citations