Jason Fangusaro

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

Pawel Buczkowicz, Christine M. Hoeman, Patricia Rakopoulos et al. · Nature Genetics · 2014 · 643 citations · Full text

Neuro-oncology, Radiation Oncology, Engineering +10

Selumetinib in paediatric patients with BRAF-aberrant or neurofibromatosis type 1-associated recurrent, refractory, or progressive low-grade glioma: a multicentre, phase 2 trial

Jason Fangusaro, Arzu Onar‐Thomas, Tina Young Poussaint et al. · The Lancet Oncology · 2019 · 472 citations · Full text

Neuro-oncology, Tumoral Pathology, Pediatric Brain Tumors +12

A phase I trial of the MEK inhibitor selumetinib (AZD6244) in pediatric patients with recurrent or refractory low-grade glioma: a Pediatric Brain Tumor Consortium (PBTC) study

Anuradha Banerjee, Regina I. Jakacki, Arzu Onar‐Thomas et al. · Neuro-Oncology · 2017 · 309 citations · Full text

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors

Jonathon Torchia, Brian Golbourn, Shengrui Feng et al. · Cancer Cell · 2016 · 251 citations · Full text

Tumor Biology, Radiation Oncology, Neuro-oncology +11

Survivin splice variants regulate the balance between proliferation and cell death

Hugo Caldas, Yuying Jiang, Michael P. Holloway et al. · Oncogene · 2005 · 202 citations

Genome Instability, Cell Division, Genetics +8