Xian‐Yun Jiao

Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction

Yosup Rew, Daqing Sun, Felix González-López de Turiso et al. · Journal of Medicinal Chemistry · 2012 · 166 citations · Full text

Identification and Functional Characterization of Allosteric Agonists for the G Protein-Coupled Receptor FFA2

TaeWeon Lee, Ralf Schwandner, Gayathri Swaminath et al. · Molecular Pharmacology · 2008 · 154 citations

The first synthetic agonists of FFA2: Discovery and SAR of phenylacetamides as allosteric modulators

Yingcai Wang, Xian‐Yun Jiao, Frank Kayser et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 100 citations · Full text

Allosteric Modulators, Drug Target, Biochemistry +8

CB-6644 Is a Selective Inhibitor of the RUVBL1/2 Complex with Anticancer Activity

Victoria A. Assimon, Yangzhong Tang, Jesse D. Vargas et al. · ACS Chemical Biology · 2019 · 91 citations

Cancer Biology, Tumor Biology, Molecular Pharmacology +17

Discovery of AM-1638: A Potent and Orally Bioavailable GPR40/FFA1 Full Agonist

Sean P. Brown, Paul J. Dransfield, Marc Vimolratana et al. · ACS Medicinal Chemistry Letters · 2012 · 88 citations · Full text

Partial Agonist 1, Pancreatic Islets, Biochemistry +12