Kynurenic Acid as a Ligand for Orphan G Protein-coupled Receptor GPR35

Jinghong Wang, Nicole Simonavicius, Xiaosu Wu, +4

Journal of Biological Chemistry

Coupling ligand structure to specific conformational switches in the β2-adrenoceptor

Xiao-Jie Yao, Charles Parnot, Xavier Deupí, +4

Nature Chemical Biology

Molecular PharmacologyBiochemistryG Protein-coupled ReceptorLigand StructureReceptor (Biochemistry) +4

Sequential Binding of Agonists to the β2 Adrenoceptor

Gayathri Swaminath, Yang K. Xiang, Tae Weon Lee, +3

Journal of Biological Chemistry

Probing the β2 Adrenoceptor Binding Site with Catechol Reveals Differences in Binding and Activation by Agonists and Partial Agonists

Gayathri Swaminath, Xavier Deupí, Tae Weon Lee, +4

Journal of Biological Chemistry

PharmacotherapyMolecular PharmacologyMedicinal ChemistryNeuroendocrine MechanismAr Activation +18

Identification and Functional Characterization of Allosteric Agonists for the G Protein-Coupled Receptor FFA2

TaeWeon Lee, Ralf Schwandner, Gayathri Swaminath, +11

Molecular Pharmacology

A Potent Class of GPR40 Full Agonists Engages the EnteroInsular Axis to Promote Glucose Control in Rodents

Jian Luo, Gayathri Swaminath, Sean P. Brown, +15

PLoS ONE

Glucose ControlGpr40 Full AgonistsInsulin SignalingGastrointestinal Peptide HormoneMolecular Pharmacology +18

Structural Basis for Apelin Control of the Human Apelin Receptor

Yingli Ma, Yang Yue, Yanbin Ma, +17

Structure

Molecular PhysiologySignal TransductionG Protein-coupled ReceptorMedicineReceptor Tyrosine Kinase +7

Identification and Pharmacological Characterization of Multiple Allosteric Binding Sites on the Free Fatty Acid 1 Receptor

Daniel C.-H. Lin, Qi Guo, Jian Luo, +12

Molecular Pharmacology

A fluorescent probe designed for studying protein conformational change

Bruce E. Cohen, Arnd Pralle, Xiao-Jie Yao, +6

Proceedings of the National Academy of Sciences

Shaker Potassium ChannelProteinlipid InteractionBiochemistryProtein FoldingNatural Sciences +10

Signaling property study of adhesion G‐protein‐coupled receptors

Jamila Gupte, Gayathri Swaminath, Jay Danao, +3

FEBS Letters

Tested Adhesion GpcrsCell AdhesionCellular PhysiologyMolecular PharmacologyCell Signaling +15