Marc Vimolratana

AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies

Sean Caenepeel, Sean P. Brown, Brian Belmontes et al. · Cancer Discovery · 2018 · 408 citations · Full text

A Potent Class of GPR40 Full Agonists Engages the EnteroInsular Axis to Promote Glucose Control in Rodents

Jian Luo, Gayathri Swaminath, Sean P. Brown et al. · PLoS ONE · 2012 · 136 citations · Full text

Glucose Control, Gpr40 Full Agonists, Insulin Signaling +20

Identification and Pharmacological Characterization of Multiple Allosteric Binding Sites on the Free Fatty Acid 1 Receptor

Daniel C.-H. Lin, Qi Guo, Jian Luo et al. · Molecular Pharmacology · 2012 · 119 citations · Full text

Discovery of AM-1638: A Potent and Orally Bioavailable GPR40/FFA1 Full Agonist

Sean P. Brown, Paul J. Dransfield, Marc Vimolratana et al. · ACS Medicinal Chemistry Letters · 2012 · 88 citations · Full text

Partial Agonist 1, Pancreatic Islets, Biochemistry +12

Discovery and Optimization of Potent GPR40 Full Agonists Containing Tricyclic Spirocycles

Yingcai Wang, Jiwen Liu, Paul J. Dransfield et al. · ACS Medicinal Chemistry Letters · 2013 · 81 citations · Full text

Combinatorial Chemistry, Molecular Physiology, Biochemistry +13