Concepedia
Statistics
Publications
19
Citations
990
H-Index
16
Active since
1999
Affiliations
Amgen (United States)(Current)
Array BioPharma (United States)
University of Exeter
GlaxoSmithKline (United Kingdom)
Texas A&M University
Paul J. Dransfield is an author at Amgen (United States) specializing in medicinal chemistry, pharmacology, and drug discovery.
Publications per year
1999–2023
A Potent Class of GPR40 Full Agonists Engages the EnteroInsular Axis to Promote Glucose Control in Rodents
Jian Luo, Gayathri Swaminath, Sean P. Brown et al. · PLoS ONE · 2012 · 136 citations · Full text
Medicine, Endocrinology, Pharmacology +17
Identification and Pharmacological Characterization of Multiple Allosteric Binding Sites on the Free Fatty Acid 1 Receptor
Daniel C.-H. Lin, Qi Guo, Jian Luo et al. · Molecular Pharmacology · 2012 · 119 citations · Full text
Activation of FFA1 mediates GLP-1 secretion in mice. Evidence for allosterism at FFA1
Yumei Xiong, Gayathri Swaminath, Qiong Cao et al. · Molecular and Cellular Endocrinology · 2013 · 90 citations
Life Sciences, Endocrinology, Physiology +11
Discovery of AM-1638: A Potent and Orally Bioavailable GPR40/FFA1 Full Agonist
Sean P. Brown, Paul J. Dransfield, Marc Vimolratana et al. · ACS Medicinal Chemistry Letters · 2012 · 89 citations · Full text
Medicine, Medicinal Chemistry, Pharmacology +17
Discovery and Optimization of Potent GPR40 Full Agonists Containing Tricyclic Spirocycles
Yingcai Wang, Jiwen Liu, Paul J. Dransfield et al. · ACS Medicinal Chemistry Letters · 2013 · 81 citations · Full text
Pharmacy, Medicinal Chemistry, Pharmacology +17
1–5 of 19