Sandra J. Hoffman - Concepedia

Author

Sandra J. Hoffman

Also Known As

Hoffman, S.J., S Hoffman, S J Hoffman, S.J Hoffman, S.J. Hoffman, SJ Hoffman, Sandra Hoffman, Sandra J Hoffman, Sandra J. Hoffman, Sandra Josephs Hoffman

Publications

2.3K

Citations

H-Index

Concepts

All Affiliations

GlaxoSmithKline (United States)New Frontier Fox Chase Cancer Center GlaxoSmithKline (United Kingdom)South College

About

Sandra J. Hoffman is an author at GlaxoSmithKline (United States) specializing in medicine, pharmacology, and osteoporosis.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	17	18	1.9K
2	Cell Biology	8	8	1.2K
3	Natural Sciences	6	6	1.2K
4	Health Sciences	4	4	338
5	Biochemistry	3	3	415

Sandra J. Hoffman

Publications

2.2K

Citations

H-Index

Page 1

	Year	Citations
Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases Philip A. Harris, Scott B. Berger, Jae Uk Jeong, Journal of Medicinal Chemistry Drug TargetImmunologyCell DeathPharmacotherapyInflammation	2017	464
DNA-Encoded Library Screening Identifies Benzo[<i>b</i>][1,4]oxazepin-4-ones as Highly Potent and Monoselective Receptor Interacting Protein 1 Kinase Inhibitors Philip A. Harris, Bryan W. King, Deepak Bandyopadhyay, Journal of Medicinal Chemistry Drug TargetImmunologyKinase InhibitorsMolecular BiologyCell Death	2016	268
Ethacrynic acid and piriprost as enhancers of cytotoxicity in drug resistant and sensitive cell lines. Kenneth D. Tew, A M Bomber, Sandra J. Hoffman PubMed Ethacrynic AcidCellular PharmacologyPharmacotherapyOxidative StressDrug Resistance	1988	212
Potent and Selective Inhibition of Human Cathepsin K Leads to Inhibition of Bone Resorption In Vivo in a Nonhuman Primate George B. Stroup, Michael W. Lark, Daniel F. Veber, Journal of Bone and Mineral Research	2001	153
Intermittent treatment with parathyroid hormone (PTH) as well as a non-peptide small molecule agonist of the PTH1 receptor inhibits adipocyte differentiation in human bone marrow stromal cells David J. Rickard, Feilan Wang, Alexandro Rodríguez-Rojas, Bone Intermittent TreatmentMetabolic SyndromeMedicinePhysiologyPth1 Receptor Inhibits	2006	149
Discovery of Small Molecule RIP1 Kinase Inhibitors for the Treatment of Pathologies Associated with Necroptosis Philip A. Harris, Deepak Bandyopadhyay, Scott B. Berger, ACS Medicinal Chemistry Letters Pathologies AssociatedApoptosisImmunologyCell DeathMolecular Biology	2013	135
Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock Pratyusha Mandal, Yanjun Feng, John D. Lyons, Immunity InflammationAnti-inflammatoryDrive Tissue DamageMedicineApoptosis	2018	126
Idoxifene: A Novel Selective Estrogen Receptor Modulator Prevents Bone Loss and Lowers Cholesterol Levels in Ovariectomized Rats and Decreases Uterine Weight in Intact Rats Mark Nuttall, Jeremy N. Bradbeer, George B. Stroup, Endocrinology Hormonal ContraceptiveGynecologyDecreases Uterine WeightUterine Wet WeightOsteoporosis	1998	88
An orally active calcium-sensing receptor antagonist that transiently increases plasma concentrations of PTH and stimulates bone formation Sanjay Kumar, Christopher Matheny, Sandra J. Hoffman, Bone Plasma ConcentrationsMedicinePhysiologyParathyroid HormoneOsteoarthritis	2009	79
A potent small molecule, nonpeptide inhibitor of cathepsin K (SB 331750) prevents bone matrix resorption in the ovariectomized rat Michael W. Lark, George B. Stroup, Ian E. James, Bone SclerostinPotent Small MoleculeBone Morphogenic ProteinMedicineSb 331750	2002	78

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