Steven E. Hall

(<i>S</i>)-13-[(Dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16,21-dimetheno- 1<i>H</i>,13<i>H</i>-dibenzo[<i>e</i>,<i>k</i>]pyrrolo[3,4-<i>h</i>][1,4,13]oxadiazacyclohexadecene-1,3(2<i>H</i>)-dione (LY333531) and Related Analogues:  Isozyme Selective Inhibitors of Protein Kinase Cβ

Michael R. Jirousek, James R. Gillig, Cécile Gonzalez et al. · Journal of Medicinal Chemistry · 1996 · 336 citations · Full text

Pkc Isozymes, Bioorganic Chemistry, Endothelial Cells +17

SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK

Yutaka Okawa, Teru Hideshima, Paul M. Steed et al. · Blood · 2008 · 208 citations · Full text

Discovery of Novel 2-Aminobenzamide Inhibitors of Heat Shock Protein 90 as Potent, Selective and Orally Active Antitumor Agents

Kenneth H. Huang, James M. Veal, R. Patrick Fadden et al. · Journal of Medicinal Chemistry · 2009 · 188 citations · Full text

Drug Target, Pharmacotherapy, Chemical Biology +16

SNX2112, a Synthetic Heat Shock Protein 90 Inhibitor, Has Potent Antitumor Activity against HER Kinase–Dependent Cancers

Sarat Chandarlapaty, Ayana Sawai, Qing Ye et al. · Clinical Cancer Research · 2008 · 184 citations

Small molecule inhibitors of Hsp90 potently affect inflammatory disease pathways and exhibit activity in models of rheumatoid arthritis

John W. Rice, James M. Veal, R. Patrick Fadden et al. · Arthritis & Rheumatism · 2008 · 134 citations