R. Patrick Fadden

Discovery of Novel 2-Aminobenzamide Inhibitors of Heat Shock Protein 90 as Potent, Selective and Orally Active Antitumor Agents

Kenneth H. Huang, James M. Veal, R. Patrick Fadden et al. · Journal of Medicinal Chemistry · 2009 · 188 citations · Full text

Drug Target, Pharmacotherapy, Chemical Biology +16

Small molecule inhibitors of Hsp90 potently affect inflammatory disease pathways and exhibit activity in models of rheumatoid arthritis

John W. Rice, James M. Veal, R. Patrick Fadden et al. · Arthritis & Rheumatism · 2008 · 134 citations

Discovery of benzamide tetrahydro-4H-carbazol-4-ones as novel small molecule inhibitors of Hsp90

Thomas E. Barta, James M. Veal, John W. Rice et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 89 citations

Combinatorial Chemistry, Medicinal Chemistry, Drug Target +10

Discovery of novel aminoquinazolin-7-yl 6,7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90

Kenneth H. Huang, Thomas E. Barta, John W. Rice et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 15 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +8