James M. Veal

Discovery of 5-[[4-[(2,3-Dimethyl-2<i>H</i>-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular Endothelial Growth Factor Receptor Inhibitor

Philip A. Harris, Amogh Boloor, Mui Cheung et al. · Journal of Medicinal Chemistry · 2008 · 342 citations · Full text

A Nucleic Acid Triple Helix Formed by a Peptide Nucleic Acid-DNA Complex

Laurie Betts, John A. Josey, James M. Veal et al. · Science · 1995 · 296 citations

Crystal Structure, Dna, Structural Bioinformatics +16

DAPI (4',6-diamidino-2-phenylindole) binds differently to DNA and RNA: minor-groove binding at AT sites and intercalation at AU sites

Farial A. Tanious, James M. Veal, Henryk Buczak et al. · Biochemistry · 1992 · 272 citations

Oxindole-Based Inhibitors of Cyclin-Dependent Kinase 2 (CDK2):  Design, Synthesis, Enzymatic Activities, and X-ray Crystallographic Analysis

H. Neal Bramson, J. Corona, Stephen T. Davis et al. · Journal of Medicinal Chemistry · 2001 · 267 citations · Full text

Oxindole-based Inhibitors, Oxindole-based Compounds, Ligand Docking +16

Binding Mode of the 4-Anilinoquinazoline Class of Protein Kinase Inhibitor:  X-ray Crystallographic Studies of 4-Anilinoquinazolines Bound to Cyclin-Dependent Kinase 2 and p38 Kinase

Lisa M. Shewchuk, Anne M. Hassell, Bruce Wisely et al. · Journal of Medicinal Chemistry · 1999 · 231 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +15