Farial A. Tanious

Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors

Martin L. Read, R. John Harrison, Bárbara Romagnoli et al. · Proceedings of the National Academy of Sciences · 2001 · 484 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

DAPI (4',6-diamidino-2-phenylindole) binds differently to DNA and RNA: minor-groove binding at AT sites and intercalation at AU sites

Farial A. Tanious, James M. Veal, Henryk Buczak et al. · Biochemistry · 1992 · 275 citations

Life Sciences, Molecular Biology, Molecular Biophysics +8

DNA sequence dependent binding modes of 4',6-diamidino-2-phenylindole (DAPI)

W. David Wilson, Farial A. Tanious, H. Bartoń et al. · Biochemistry · 1990 · 218 citations

Life Sciences, Biochemistry, Molecular Biology +17

Trisubstituted Acridines as G-quadruplex Telomere Targeting Agents. Effects of Extensions of the 3,6- and 9-Side Chains on Quadruplex Binding, Telomerase Activity, and Cell Proliferation

Michael J. Moore, Christoph Schultes, Javier Cuesta et al. · Journal of Medicinal Chemistry · 2005 · 202 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

Structure-specific recognition of quadruplex DNA by organic cations: Influence of shape, substituents and charge

Elizabeth W. White, Farial A. Tanious, Mohamed A. Ismail et al. · Biophysical Chemistry · 2006 · 195 citations

Pharmacy, Biochemistry, Chemistry +16