R. John Harrison

Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors

Martin L. Read, R. John Harrison, Bárbara Romagnoli et al. · Proceedings of the National Academy of Sciences · 2001 · 481 citations · Full text

Trisubstituted Acridine Derivatives as Potent and Selective Telomerase Inhibitors

R. John Harrison, Javier Cuesta, Gianni Chessari et al. · Journal of Medicinal Chemistry · 2003 · 182 citations · Full text

Bioorganic Chemistry, Telomerase Activity, Molecular Biology +19

Human telomerase inhibition by substituted acridine derivatives

R. John Harrison, Sharon Gowan, Lloyd R. Kèlland et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 159 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Natural Sciences +7

Inhibition of the Bloom's and Werner's Syndrome Helicases by G-Quadruplex Interacting Ligands

Jiliang Li, R. John Harrison, Anthony P. Reszka et al. · Biochemistry · 2001 · 99 citations · Full text

Evaluation of by disubstituted acridone derivatives as telomerase inhibitors: the importance of G-quadruplex binding

R. John Harrison, Anthony P. Reszka, Shozeb Haider et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 78 citations · Full text

Disubstituted Acridone Derivatives, Medicinal Chemistry, Bioorganic Chemistry +8