James R. Gillig

(<i>S</i>)-13-[(Dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16,21-dimetheno- 1<i>H</i>,13<i>H</i>-dibenzo[<i>e</i>,<i>k</i>]pyrrolo[3,4-<i>h</i>][1,4,13]oxadiazacyclohexadecene-1,3(2<i>H</i>)-dione (LY333531) and Related Analogues:  Isozyme Selective Inhibitors of Protein Kinase Cβ

Michael R. Jirousek, James R. Gillig, Cécile Gonzalez et al. · Journal of Medicinal Chemistry · 1996 · 338 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

Structure of a dehydratase–isomerase from the bacterial pathway for biosynthesis of unsaturated fatty acids: two catalytic activities in one active site

Minsun Leesong, Barry Henderson, James R. Gillig et al. · Structure · 1996 · 272 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, in Human Cancer Cells

Bo Tan, Debra A. Young, Zhao-Hai Lu et al. · Journal of Biological Chemistry · 2012 · 174 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Acyclic N-(azacycloalkyl)bisindolylmaleimides: isozyme selective inhibitors of PKCβ

Margaret M. Faul, James R. Gillig, Michael R. Jirousek et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 90 citations · Full text

Life Sciences, Chemistry, Pharmacology +9

Discovery and characterization of LY2784544, a small-molecule tyrosine kinase inhibitor of JAK2V617F

Liandong Ma, Joshua R. Clayton, Richard A. Walgren et al. · Blood Cancer Journal · 2013 · 66 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16