Structure of a dehydratase–isomerase from the bacterial pathway for biosynthesis of unsaturated fatty acids: two catalytic activities in one active site

Basic local alignment search tool

Stephen F. Altschul, Warren Gish, Webb Miller et al. · Journal of Molecular Biology · 1990 · 94.5K citations

Life Sciences, Bioinformatics, Sequence Analysis +3

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Julie Thompson, Desmond G. Higgins, Toby J. Gibson · Nucleic Acids Research · 1994 · 64.9K citations · Full text

Life Sciences, Bioinformatics, Sequence Analysis +14

PROCHECK: a program to check the stereochemical quality of protein structures

Roman A. Laskowski, Malcolm W. MacArthur, D. S. Moss et al. · Journal of Applied Crystallography · 1993 · 24.6K citations

Life Sciences, Biochemistry, Bioinformatics +9

The CCP4 suite: programs for protein crystallography

Number Collaborative Computational Project · Acta Crystallographica Section D Biological Crystallography · 1994 · 17.3K citations

Life Sciences, Biochemistry, Biophysics +15

Improved methods for building protein models in electron density maps and the location of errors in these models

T. Alwyn Jones, Jin-yu Zou, Sandra W. Cowan et al. · Acta Crystallographica Section A Foundations of Crystallography · 1991 · 12.7K citations

Life Sciences, Biochemistry, Biomolecular Modeling +16