Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, in Human Cancer Cells

Bo Tan, Debra A. Young, Zhao-Hai Lu, +13

Journal of Biological Chemistry

GlycobiologyNad+ BiosynthesisMetabolic RemodelingPharmacological InhibitionSerine Biosynthesis +17

The Folate Pathway Inhibitor Pemetrexed Pleiotropically Enhances Effects of Cancer Immunotherapy

David Schaer, Sandaruwan Geeganage, Nelusha Amaladas, +24

Clinical Cancer Research

Derivatization of the tricarboxylic acid intermediates with O-benzylhydroxylamine for liquid chromatography–tandem mass spectrometry detection

Bo Tan, ZhaoHai Lu, Sucai Dong, +2

Analytical Biochemistry

Chemical MeasurementEngineeringBiochemistryMedicineTricarboxylic Acid Intermediates +8

Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, Leads to Altered Carbohydrate Metabolism in Cancer Cells

Bo Tan, Sucai Dong, Robert L. Shepard, +5

Journal of Biological Chemistry

Aldo-keto ReductaseChemoprevention StrategyNad+ BiosynthesisMetabolic RemodelingChemical Biology +16

Autophagy-related proteins LC3 and Beclin-1 impact the efficacy of chemoradiation on esophageal squamous cell carcinoma

Yongshun Chen, Xiaohong Li, Xiao‐Yuan Wu, +6

Pathology - Research and Practice

Cell AutophagyEsophageal CancerMedicineAutophagyCell Death +7

Discovery of a Highly Selective NAMPT Inhibitor That Demonstrates Robust Efficacy and Improved Retinal Toxicity with Nicotinic Acid Coadministration

Genshi Zhao, Colin F. Green, Yu‐Hua Hui, +18

Molecular Cancer Therapeutics

A novel dendrimer-type m-terphenyl substituent for the kinetic stabilization of highly reactive species

Kei Goto, Gaku Yamamoto, Bo Tan, +1

Tetrahedron Letters

Combinatorial ChemistryEngineeringChemical DerivativeOrganic ChemistryReactivity (Chemistry) +6

Thermoregulated ionic liquids and their application for the hydroformylation of 1‐dodecene catalyzed by Rh/TPPTS complex

Bo Tan, Jingyang Jiang, Yanhua Wang, +3

Applied Organometallic Chemistry

Chemical TechnologyInorganic ChemistryChemical EngineeringEngineeringIonic Liquids +13

Monensin Mediates a Rapid and Selective Transport of Pb2+

Shawn A. Hamidinia, Olga Shimelis, Bo Tan, +5

Journal of Biological Chemistry

Promising outcomes of definitive chemoradiation and cetuximab for patients with esophageal squamous cell carcinoma

Yongshun Chen, Xiao‐Yuan Wu, Shanshan Bu, +7

Cancer Science