Nelusha Amaladas

The CDK4/6 Inhibitor Abemaciclib Induces a T Cell Inflamed Tumor Microenvironment and Enhances the Efficacy of PD-L1 Checkpoint Blockade

David Schaer, Richard P. Beckmann, Jack Dempsey et al. · Cell Reports · 2018 · 418 citations · Full text

The Folate Pathway Inhibitor Pemetrexed Pleiotropically Enhances Effects of Cancer Immunotherapy

David Schaer, Sandaruwan Geeganage, Nelusha Amaladas et al. · Clinical Cancer Research · 2019 · 121 citations

Effects of checkpoint kinase 1 inhibition by prexasertib on the tumor immune microenvironment of head and neck squamous cell carcinoma

Ritu Chaudhary, Robbert J.C. Slebos, Feifei Song et al. · Molecular Carcinogenesis · 2020 · 25 citations · Full text

Treatment with a VEGFR-2 antibody results in intra-tumor immune modulation and enhances anti-tumor efficacy of PD-L1 blockade in syngeneic murine tumor models

Yanxia Li, Nelusha Amaladas, Marguerita O’Mahony et al. · PLoS ONE · 2022 · 18 citations · Full text

Immunology, Pathology, Vegfr-2 Antibody Results +17

Abstract 4549: Pemetrexed enhances anti-tumor efficacy of PD1 pathway blockade by promoting intra tumor immune response via immunogenic tumor cell death and T cell intrinsic mechanisms

Ruslan D. Novosiadly, David Schaer, Nelusha Amaladas et al. · Cancer Research · 2018 · 14 citations

Immunology, Immune Regulation, Immunoediting +21