Joerg Bussenius

Novel Carboxamide-Based Allosteric MEK Inhibitors: Discovery and Optimization Efforts toward XL518 (GDC-0973)

Kenneth D. Rice, Naing Aay, Neel K. Anand et al. · ACS Medicinal Chemistry Letters · 2012 · 161 citations · Full text

Drug Target, Erk/map Kinase Cascade, Structural Insight +21

Discovery of XL888: A novel tropane-derived small molecule inhibitor of HSP90

Joerg Bussenius, Charles M. Blazey, Naing Aay et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 77 citations · Full text

Molecular Pharmacology, Protein Function, Medicine +7

Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists

Shenping Liu, Leslie Dakin, Xing Li et al. · Scientific Reports · 2016 · 60 citations · Full text

Pyrazolopyrimidines as dual Akt/p70S6K inhibitors

Kenneth D. Rice, Moon H. Kim, Joerg Bussenius et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 27 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Medicine +7

Design and evaluation of a series of pyrazolopyrimidines as p70S6K inhibitors

Joerg Bussenius, Neel K. Anand, Charles M. Blazey et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 24 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +11