Ken Grime - Concepedia

Author

Ken Grime

Loughborough University

Also Known As

Ken Grime

Publications

1.5K

Citations

H-Index

Concepts

All Affiliations

Loughborough University AstraZeneca (Sweden)AstraZeneca (United Kingdom)AstraZeneca (United States)AstraZeneca (Brazil)

About

Ken Grime is an author at Loughborough University specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	9	9	202
2	Natural Sciences	3	3	62
3	Biochemistry	2	2	77
4	Engineering	1	1	48
5	Health Sciences	1	1	21

Ken Grime

Publications

983

Citations

H-Index

Page 1

	Year	Citations
Use of Hepatocytes to Assess the Contribution of Hepatic Uptake to Clearance in Vivo Matthew G. Soars, Ken Grime, Joanne L. Sproston, Drug Metabolism and Disposition	2007	142
EVALUATION OF TIME-DEPENDENT CYTOCHROME P450 INHIBITION USING CULTURED HUMAN HEPATOCYTES Dermot F. McGinnity, Amanda J. Berry, Jane R. Kenny, Drug Metabolism and Disposition	2006	99
AUTOMATED ASSESSMENT OF TIME-DEPENDENT INHIBITION OF HUMAN CYTOCHROME P450 ENZYMES USING LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY ANALYSIS Anthony C. Atkinson, Jane R. Kenny, Ken Grime Drug Metabolism and Disposition	2005	96
Metabolic screening in vitro: metabolic stability, CYP inhibition and induction Robert J. Riley, Ken Grime Drug Discovery Today Technologies BiochemistryMedicineMetabolic ScreeningMetabolic EngineeringMetabolic Regulation	2004	56
Species Differences in Biliary Clearance and Possible Relevance of Hepatic Uptake and Efflux Transporters Involvement Ken Grime, Stuart W. Paine Drug Metabolism and Disposition	2012	55
HepaRG Cells as Human-Relevant In Vitro Model to Study the Effects of Inflammatory Stimuli on Cytochrome P450 Isoenzymes Katarina Rubin, Annika Janefeldt, Linda Andersson, Drug Metabolism and Disposition	2014	52
Preclinical Development Handbook: ADME and Biopharmaceutical Properties Harvey J. Clewell, Robert J. Riley, Jane R. Kenny, Pharmaceutical ScienceEngineeringPreclinical Development HandbookBiotechnologyPharmaceutical Biotechnology	2007	48
The Development of a Cocktail CYP2B6, CYP2C8, and CYP3A5 Inhibition Assay and a Preliminary Assessment of Utility in a Drug Discovery Setting Colm P. O’Donnell, Ken Grime, Paul Courtney, Drug Metabolism and Disposition	2006	38
Translational Model to Predict Pulmonary Pharmacokinetics and Efficacy in Man for Inhaled Bronchodilators Ramon Hendrickx, Eva Lamm Bergström, David Janzén, CPT Pharmacometrics & Systems Pharmacology	2017	38
The Use of HepaRG and Human Hepatocyte Data in Predicting CYP Induction Drug-Drug Interactions via Static Equation and Dynamic Mechanistic Modelling Approaches Ken Grime, Douglas Ferguson, Robert J. Riley Current Drug Metabolism	2010	29

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