Concepedia

Species Differences in Biliary Clearance and Possible Relevance of Hepatic Uptake and Efflux Transporters Involvement

Ken Grime, Stuart W. Paine

Drug Metabolism and Disposition · 2012 · 55 citations · 78 references

DOI

Concepts

References

78

The Pharmacological Basis of Therapeutics

American Journal of Health-System Pharmacy · 1976 · 8.2K citations

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OATP and P-Glycoprotein Transporters Mediate the Cellular Uptake and Excretion of Fexofenadine

Mirjana Cvetković, Brenda F. Leake, Martin F. Fromm et al. · Drug Metabolism and Disposition · 1999 · 595 citations

, , +17

Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 670 Drug Compounds

R. Scott Obach, Franco Lombardo, Nigel J. Waters · Drug Metabolism and Disposition · 2008 · 454 citations

, , +14

Physiologically Based Pharmacokinetic Modeling to Predict Transporter-Mediated Clearance and Distribution of Pravastatin in Humans

Takao Watanabe, Hiroyuki Kusuhara, Kazuya Maeda et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 350 citations

, , +17

Formation of extensive canalicular networks by rat hepatocytes cultured in collagen-sandwich configuration

Edward L. LeCluyse, Kenneth L. Audus, Jerome Hochman · American Journal of Physiology-Cell Physiology · 1994 · 261 citations

, , +15