Stuart W. Paine

From ATP to AZD6140: The discovery of an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis

Brian Springthorpe, A. S. Bailey, Patrick Barton et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 233 citations · Full text

Thrombosis, Platelet Aggregation Inhibitors, Biochemistry +8

Prediction of the Pharmacokinetics of Atorvastatin, Cerivastatin, and Indomethacin Using Kinetic Models Applied to Isolated Rat Hepatocytes

Stuart W. Paine, Alison J. Parker, Philip Gardiner et al. · Drug Metabolism and Disposition · 2008 · 105 citations

Prediction of Human Renal Clearance from Preclinical Species for a Diverse Set of Drugs That Exhibit Both Active Secretion and Net Reabsorption

Stuart W. Paine, Karelle Ménochet, Rebecca Denton et al. · Drug Metabolism and Disposition · 2011 · 97 citations

Hit-to-lead studies: the discovery of potent, orally active, thiophenecarboxamide IKK-2 inhibitors

Andrew Baxter, Steve Brough, Anne Cooper et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 90 citations

Medicinal Chemistry, Thiophenecarboxamide Ikk-2 Inhibitors, Hit Identification +11

In Silico Human and Rat<i>V</i>_ssQuantitative Structure−Activity Relationship Models

M. Paul Gleeson, Nigel J. Waters, Stuart W. Paine et al. · Journal of Medicinal Chemistry · 2006 · 78 citations