Steve Brough

Hit-to-Lead studies: The discovery of potent adamantane amide P2X7 receptor antagonists

Andrew Baxter, Janice Bent, Keith Bowers et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 117 citations · Full text

Drug Target, Biochemistry, Functional Selectivity +9

Hit-to-lead studies: the discovery of potent, orally active, thiophenecarboxamide IKK-2 inhibitors

Andrew Baxter, Steve Brough, Anne Cooper et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 90 citations

Medicinal Chemistry, Thiophenecarboxamide Ikk-2 Inhibitors, Hit Identification +11

Hit-to-Lead studies: The discovery of potent, orally bioavailable triazolethiol CXCR2 receptor antagonists

Andrew Baxter, Colin Bennion, Janice Bent et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 46 citations · Full text

Pharmaceutical Science, Drug Target, Pharmacology +7

Substituted indole-1-acetic acids as potent and selective CRTh2 antagonists—discovery of AZD1981

Tim Luker, Roger V. Bonnert, Steve Brough et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 40 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +9

Investigating Scale-Up and Further Applications of DABAL-Me₃Promoted Amide Synthesis

Darren S. Lee, Zacharias Amara, Martyn Poliakoff et al. · Organic Process Research & Development · 2015 · 20 citations