Patrick Barton

A Comparison of Physiochemical Property Profiles of Development and Marketed Oral Drugs

Mark C. Wenlock, Rupert P. Austin, Patrick Barton et al. · Journal of Medicinal Chemistry · 2003 · 530 citations

Molecular Pharmacology, Rigorous Selection Pressures, Physiochemical Property Profiles +13

The Influence of Nonspecific Microsomal Binding on Apparent Intrinsic Clearance, and Its Prediction from Physicochemical Properties

Rupert P. Austin, Patrick Barton, Scott L. Cockroft et al. · Drug Metabolism and Disposition · 2002 · 399 citations

From ATP to AZD6140: The discovery of an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis

Brian Springthorpe, A. S. Bailey, Patrick Barton et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 233 citations · Full text

Thrombosis, Platelet Aggregation Inhibitors, Biochemistry +8

THE BINDING OF DRUGS TO HEPATOCYTES AND ITS RELATIONSHIP TO PHYSICOCHEMICAL PROPERTIES

Rupert P. Austin, Patrick Barton, Sarfraz Mohmed et al. · Drug Metabolism and Disposition · 2004 · 170 citations

Application of In Silico, In Vitro and Preclinical Pharmacokinetic Data for the Effective and Efficient Prediction of Human Pharmacokinetics

K. Grime, Patrick Barton, Dermot F. McGinnity · Molecular Pharmaceutics · 2012 · 74 citations

Dmpk Scientists, Medicinal Chemistry, Preclinical Pharmacokinetic Data +15