Sudeep Prajapati

H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers

Michael Seiler, Akihide Yoshimi, Rachel Darman et al. · Nature Medicine · 2018 · 510 citations · Full text

Life Sciences, Molecular Biology, Oncology +15

H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma

Jaya Julie Joshi, Heather Coffey, Erik Corcoran et al. · Cancer Research · 2017 · 151 citations

Medicine, Oncology, Pharmacology +15

Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A–SF3b complex

Teng Teng, Jennifer Tsai, Xiaoling Puyang et al. · Nature Communications · 2017 · 149 citations · Full text

Life Sciences, Biology, Molecular Biology +16

Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ERαWT and ERαMUT Breast Cancer

Xiaoling Puyang, Craig Furman, Guo Zhu Zheng et al. · Cancer Discovery · 2018 · 112 citations

Medicine, Oncology, Pharmacology +17

Annulation of Thioimidates and Vinyl Carbodiimides to Prepare 2-Aminopyrimidines, Competent Nucleophiles for Intramolecular Alkyne Hydroamination. Synthesis of (−)-Crambidine

Nicholas R. Perl, Nathan D. Ide, Sudeep Prajapati et al. · Journal of the American Chemical Society · 2010 · 62 citations

Pharmacy, Chemistry, Medicinal Chemistry +6