Chun Sing Li

The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K

Jacques Yves Gauthier, Nathalie Chauret, Wanda Cromlish et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 473 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Development of a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor (MK-8245) to Establish a Therapeutic Window for the Treatment of Diabetes and Dyslipidemia

Renata M. Oballa, Liette Belair, W. Cameron Black et al. · Journal of Medicinal Chemistry · 2011 · 142 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Trifluoroethylamines as amide isosteres in inhibitors of cathepsin K

W. Cameron Black, Christopher I. Bayly, Dana Davis et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 140 citations

Life Sciences, Chemistry, Medicinal Chemistry +14

Difluoroethylamines as an amide isostere in inhibitors of cathepsin K

Élise Isabel, Christophe Mellon, Michael J. Boyd et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 111 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +12

The Structural Basis for the Selectivity of Benzotriazole Inhibitors of PTP1B

Giovanna Scapin, Sangita B. Patel, Joseph W. Becker et al. · Biochemistry · 2003 · 105 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17