Takashi Kawasuji

<i>In Vitro</i>Antiretroviral Properties of S/GSK1349572, a Next-Generation HIV Integrase Inhibitor

Masanori Kobayashi, Tomokazu Yoshinaga, Takahiro Seki et al. · Antimicrobial Agents and Chemotherapy · 2010 · 377 citations · Full text

Life Sciences, Pharmacokinetics, Pharmacology +17

Carbamoyl Pyridone HIV-1 Integrase Inhibitors 3. A Diastereomeric Approach to Chiral Nonracemic Tricyclic Ring Systems and the Discovery of Dolutegravir (S/GSK1349572) and (S/GSK1265744)

Brian A. Johns, Takashi Kawasuji, Jason G. Weatherhead et al. · Journal of Medicinal Chemistry · 2013 · 184 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Antiviral Characteristics of GSK1265744, an HIV Integrase Inhibitor Dosed Orally or by Long-Acting Injection

Tomokazu Yoshinaga, Masanori Kobayashi, Takahiro Seki et al. · Antimicrobial Agents and Chemotherapy · 2014 · 100 citations · Full text

Life Sciences, Pharmacokinetics, Pharmacology +17

Carbamoyl Pyridone HIV-1 Integrase Inhibitors. 2. Bi- and Tricyclic Derivatives Result in Superior Antiviral and Pharmacokinetic Profiles

Takashi Kawasuji, Brian A. Johns, Hiroshi Yoshida et al. · Journal of Medicinal Chemistry · 2013 · 92 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

A platform for designing HIV integrase inhibitors. Part 2: A two-metal binding model as a potential mechanism of HIV integrase inhibitors

Takashi Kawasuji, Masahiro Fuji, Tomokazu Yoshinaga et al. · Bioorganic & Medicinal Chemistry · 2006 · 82 citations

Pharmacy, Medicinal Chemistry, Molecular Biology +16