Brian A. Johns

<i>In Vitro</i>Antiretroviral Properties of S/GSK1349572, a Next-Generation HIV Integrase Inhibitor

Masanori Kobayashi, Tomokazu Yoshinaga, Takahiro Seki et al. · Antimicrobial Agents and Chemotherapy · 2010 · 377 citations · Full text

Life Sciences, Pharmacokinetics, Pharmacology +17

Augmentation of response and remission to serial intravenous subanesthetic ketamine in treatment resistant depression

Paulo Shiroma, Brian A. Johns, Michael A. Kuskowski et al. · Journal of Affective Disorders · 2013 · 224 citations

Medicine, Pharmacology, Psychiatry +14

Dolutegravir (S/GSK1349572) Exhibits Significantly Slower Dissociation than Raltegravir and Elvitegravir from Wild-Type and Integrase Inhibitor-Resistant HIV-1 Integrase-DNA Complexes

Kendra E. Hightower, Ruolan Wang, Felix Deanda et al. · Antimicrobial Agents and Chemotherapy · 2011 · 223 citations

Life Sciences, Infectious Diseases, Molecular Biology +17

Total Synthesis of (+)-Discodermolide

James A. Marshall, Brian A. Johns · The Journal of Organic Chemistry · 1998 · 193 citations

Natural Sciences, Chemistry, Medicinal Chemistry +11

Carbamoyl Pyridone HIV-1 Integrase Inhibitors 3. A Diastereomeric Approach to Chiral Nonracemic Tricyclic Ring Systems and the Discovery of Dolutegravir (S/GSK1349572) and (S/GSK1265744)

Brian A. Johns, Takashi Kawasuji, Jason G. Weatherhead et al. · Journal of Medicinal Chemistry · 2013 · 184 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17