Brian A. Johns

<i>In Vitro</i>Antiretroviral Properties of S/GSK1349572, a Next-Generation HIV Integrase Inhibitor

Masanori Kobayashi, Tomokazu Yoshinaga, Takahiro Seki et al. · Antimicrobial Agents and Chemotherapy · 2010 · 371 citations · Full text

Neurovirology, Drug Discovery, Medicine +14

Augmentation of response and remission to serial intravenous subanesthetic ketamine in treatment resistant depression

Paulo Shiroma, Brian A. Johns, Michael A. Kuskowski et al. · Journal of Affective Disorders · 2013 · 221 citations

Psychiatry, Addiction, Treatment Resistant Depression +14

Dolutegravir (S/GSK1349572) Exhibits Significantly Slower Dissociation than Raltegravir and Elvitegravir from Wild-Type and Integrase Inhibitor-Resistant HIV-1 Integrase-DNA Complexes

Kendra E. Hightower, Ruolan Wang, Felix Deanda et al. · Antimicrobial Agents and Chemotherapy · 2011 · 221 citations

Immunology, Molecular Biology, Slower Dissociation +18

Total Synthesis of (+)-Discodermolide

James A. Marshall, Brian A. Johns · The Journal of Organic Chemistry · 1998 · 192 citations

Cross-coupling Reaction, Engineering, Resultant Epoxy Alcohols +11

Carbamoyl Pyridone HIV-1 Integrase Inhibitors 3. A Diastereomeric Approach to Chiral Nonracemic Tricyclic Ring Systems and the Discovery of Dolutegravir (S/GSK1349572) and (S/GSK1265744)

Brian A. Johns, Takashi Kawasuji, Jason G. Weatherhead et al. · Journal of Medicinal Chemistry · 2013 · 181 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +15