Kendra E. Hightower

Dolutegravir (S/GSK1349572) Exhibits Significantly Slower Dissociation than Raltegravir and Elvitegravir from Wild-Type and Integrase Inhibitor-Resistant HIV-1 Integrase-DNA Complexes

Kendra E. Hightower, Ruolan Wang, Felix Deanda et al. · Antimicrobial Agents and Chemotherapy · 2011 · 221 citations

Immunology, Molecular Biology, Slower Dissociation +18

H-Ras Peptide and Protein Substrates Bind Protein Farnesyltransferase as an Ionized Thiolate

Kendra E. Hightower, Chih-chin Huang, Patrick J. Casey et al. · Biochemistry · 1998 · 91 citations

N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3

Richard Angell, Francis Atkinson, Murray J. B. Brown et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 90 citations · Full text

Medicinal Chemistry, Medicine, Rational Drug Design +4

Mechanistic Studies of Rat Protein Farnesyltransferase Indicate an Associative Transition State

Chih-chin Huang, Kendra E. Hightower, Carol A. Fierke · Biochemistry · 2000 · 71 citations

Design and effective synthesis of novel templates, 3,7-diphenyl-4-amino-thieno and furo-[3,2-c]pyridines as protein kinase inhibitors and in vitro evaluation targeting angiogenetic kinases

Yasushi Miyazaki, Masato Nakano, Hideyuki Sato et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 58 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Novel Templates +10