Felix Deanda

Dolutegravir (S/GSK1349572) Exhibits Significantly Slower Dissociation than Raltegravir and Elvitegravir from Wild-Type and Integrase Inhibitor-Resistant HIV-1 Integrase-DNA Complexes

Kendra E. Hightower, Ruolan Wang, Felix Deanda et al. · Antimicrobial Agents and Chemotherapy · 2011 · 221 citations

Immunology, Molecular Biology, Slower Dissociation +18

Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity

Stanley D. Chamberlain, Anikó M. Redman, Joseph W. Wilson et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 57 citations · Full text

Medicinal Chemistry, Biochemistry, Natural Sciences +8

Dolutegravir Interactions with HIV-1 Integrase-DNA: Structural Rationale for Drug Resistance and Dissociation Kinetics

Felix Deanda, Kendra E. Hightower, Robert T. Nolte et al. · PLoS ONE · 2013 · 56 citations · Full text

Immunology, Molecular Biology, Pathology +17

Discovery of Bioavailable 4,4-Disubstituted Piperidines as Potent Ligands of the Chemokine Receptor 5 and Inhibitors of the Human Immunodeficiency Virus-1

Wieslaw M. Kazmierski, Christopher Aquino, Brian A. Chauder et al. · Journal of Medicinal Chemistry · 2008 · 32 citations · Full text

Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase

Stanley D. Chamberlain, Joseph W. Wilson, Felix Deanda et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 30 citations · Full text

Biochemistry, Medicine, Natural Sciences +8