Wieslaw M. Kazmierski

A new type of synthetic peptide library for identifying ligand-binding activity

Kit S. Lam, Sydney E. Salmon, Evan M. Hersh et al. · Nature · 1991 · 1.8K citations

Pharmacy, Biochemistry, Medicinal Chemistry +16

The CCR5 Receptor-Based Mechanism of Action of 873140, a Potent Allosteric Noncompetitive HIV Entry Inhibitor

Christian Watson, Stephen Jenkinson, Wieslaw M. Kazmierski et al. · Molecular Pharmacology · 2005 · 302 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Design and synthesis of conformationally constrained somatostatin analogs with high potency and specificity for .mu. opioid receptors

John T. Pelton, Wieslaw M. Kazmierski, Károly Gulya et al. · Journal of Medicinal Chemistry · 1986 · 188 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Design and synthesis of somatostatin analogs with topographical properties that lead to highly potent and specific .mu. opioid receptor antagonists with greatly reduced binding at somatostatin receptors

Wieslaw M. Kazmierski, William S. Wire, George K. Lui et al. · Journal of Medicinal Chemistry · 1988 · 132 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Topographic design of peptide neurotransmitters and hormones on stable backbone templates: relation of conformation and dynamics to bioactivity

Wieslaw M. Kazmierski, Henry I. Yamamura, Victor J. Hruby · Journal of the American Chemical Society · 1991 · 119 citations

Pharmacy, Biochemistry, Medicinal Chemistry +17