Tomokazu Yoshinaga

Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: A platform for antiviral drug design

Yehuda Goldgur, Robert Craigie, Gerson H. Cohen et al. · Proceedings of the National Academy of Sciences · 1999 · 492 citations · Full text

Hiv Integrase, Molecular Biology, Antiviral Drug +17

<i>In Vitro</i>Antiretroviral Properties of S/GSK1349572, a Next-Generation HIV Integrase Inhibitor

Masanori Kobayashi, Tomokazu Yoshinaga, Takahiro Seki et al. · Antimicrobial Agents and Chemotherapy · 2010 · 371 citations · Full text

Neurovirology, Drug Discovery, Medicine +14

In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit

Takeshi Noshi, Mitsutaka Kitano, K. Taniguchi et al. · Antiviral Research · 2018 · 358 citations · Full text

Vitro Characterization, Biochemistry, Natural Sciences +11

Carbamoyl Pyridone HIV-1 Integrase Inhibitors 3. A Diastereomeric Approach to Chiral Nonracemic Tricyclic Ring Systems and the Discovery of Dolutegravir (S/GSK1349572) and (S/GSK1265744)

Brian A. Johns, Takashi Kawasuji, Jason G. Weatherhead et al. · Journal of Medicinal Chemistry · 2013 · 181 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +15

HIV‐1 integrase inhibitory substances from <i>Coleus parvifolius</i>

Supinya Tewtrakul, Hirotsugu Miyashiro, Norio Nakamura et al. · Phytotherapy Research · 2003 · 98 citations