Jason G. Weatherhead

Carbamoyl Pyridone HIV-1 Integrase Inhibitors 3. A Diastereomeric Approach to Chiral Nonracemic Tricyclic Ring Systems and the Discovery of Dolutegravir (S/GSK1349572) and (S/GSK1265744)

Brian A. Johns, Takashi Kawasuji, Jason G. Weatherhead et al. · Journal of Medicinal Chemistry · 2013 · 181 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +15

The use of oxadiazole and triazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 1: Establishing the pharmacophore

Brian A. Johns, Jason G. Weatherhead, Scott H. Allen et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 113 citations · Full text

Medicinal Chemistry, Medicine, Antiviral Drug Development +9

1,3,4-Oxadiazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 2: SAR of the C5 position

Brian A. Johns, Jason G. Weatherhead, Scott H. Allen et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 91 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +12

Carbamoyl Pyridone HIV-1 Integrase Inhibitors. 2. Bi- and Tricyclic Derivatives Result in Superior Antiviral and Pharmacokinetic Profiles

Takashi Kawasuji, Brian A. Johns, Hiroshi Yoshida et al. · Journal of Medicinal Chemistry · 2013 · 89 citations

Antiviral Compound, Medicine, Immunology +14

The Naphthyridinone GSK364735 Is a Novel, Potent Human Immunodeficiency Virus Type 1 Integrase Inhibitor and Antiretroviral

Edward P. Garvey, Brian A. Johns, Margaret Gartland et al. · Antimicrobial Agents and Chemotherapy · 2007 · 74 citations · Full text

Naphthyridinone Gsk364735, Medicine, Human Retrovirus +13