A validated multi-matrix platform for metabolomic fingerprinting of human urine, feces and plasma using ultra-high performance liquid-chromatography coupled to hybrid orbitrap high-resolution mass spectrometry

Ellen De Paepe, Lieven Van Meulebroek, Caroline Rombouts, +6

Analytica Chimica Acta

Human UrineValidated Multi-matrix PlatformMedicineBioanalysisMass Spectrometry +11

Untargeted metabolomics of colonic digests reveals kynurenine pathway metabolites, dityrosine and 3-dehydroxycarnitine as red versus white meat discriminating metabolites

Caroline Rombouts, Lieselot Hemeryck, Thomas Van Hecke, +3

Scientific Reports

Hepatic PPARα function and lipid metabolic pathways are dysregulated in polymicrobial sepsis

Lise Van Wyngene, Tineke Vanderhaeghen, Steven Timmermans, +17

EMBO Molecular Medicine

Reducing Compounds Equivocally Influence Oxidation during Digestion of a High-Fat Beef Product, which Promotes Cytotoxicity in Colorectal Carcinoma Cell Lines

Thomas Van Hecke, An Wouters, Caroline Rombouts, +10

Journal of Agricultural and Food Chemistry

NutritionFood AnalysisPathologyVitro DigestionMeat Quality +18

Can Pulp Fibroblasts Kill Cariogenic Bacteria? Role of Complement Activation

C. Jeanneau, Pierre Rufas, Caroline Rombouts, +3

Journal of Dental Research

Dental ConditionsFibrosisComplement System ActivationVirulence FactorOral Cavity +12

Validated comprehensive metabolomics and lipidomics analysis of colon tissue and cell lines

Caroline Rombouts, Margot De Spiegeleer, Lieven Van Meulebroek, +2

Analytica Chimica Acta

Lipidomics AnalysisComprehensive MetabolomicsMedicineBioanalysisGastroenterology +7

DNA adduct profiling of in vitro colonic meat digests to map red vs. white meat genotoxicity

Lieselot Hemeryck, Caroline Rombouts, Ellen De Paepe, +1

Food and Chemical Toxicology

White Meat GenotoxicityDna Adduct ProfilingGeneticsPathogenesisPathology +7

Metabolomics-based biomarker discovery for bee health monitoring: A proof of concept study concerning nutritional stress in Bombus terrestris

Luoluo Wang, Ivan Meeus, Caroline Rombouts, +3

Scientific Reports

In vitro DNA adduct profiling to mechanistically link red meat consumption to colon cancer promotion

Lieselot Hemeryck, Caroline Rombouts, Thomas Van Hecke, +4

Toxicology Research

Genetic (In)stability of 2,6-Dichlorobenzamide Catabolism in Aminobacter sp. Strain MSH1 Biofilms under Carbon Starvation Conditions

Benjamin Horemans, Bart Raes, Hannelore Brocatus, +5

Applied and Environmental Microbiology