Comparative Analysis of Dynamic Cell Viability, Migration and Invasion Assessments by Novel Real-Time Technology and Classic Endpoint Assays

Ridha Limame, An Wouters, Bea Pauwels, +5

PLoS ONE

Pharmacological Levels of Withaferin A (Withania somnifera) Trigger Clinically Relevant Anticancer Effects Specific to Triple Negative Breast Cancer Cells

Katarzyna Szarc vel Szic, Ken Op de Beeck, Dariusz Ratman, +10

PLoS ONE

Breast OncologyChemoprevention StrategyPharmacological LevelsTumor BiologyWithaferin A +16

The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer

Christophe Deben, An Wouters, Ken Op de Beeck, +9

Oncotarget

Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress

Christophe Deben, Vanessa Deschoolmeester, Jorrit De Waele, +8

Cancers

Overcoming cetuximab resistance in HNSCC: The role of AURKB and DUSP proteins

Carolien Boeckx, Ken Op de Beeck, An Wouters, +10

Cancer Letters

Protein FunctionNatural SciencesMolecular BiologyCetuximab ResistanceDusp Proteins +3

APR-246 (PRIMA-1 MET ) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines

Christophe Deben, Filip Lardon, An Wouters, +8

Cancer Letters

Prima-1 MetParp InhibitionMedicineApoptosisPharmacology +8

The art of obtaining a high yield of cell-free DNA from urine

Elien Augustus, Kaat Van Casteren, Laure Sorber, +9

PLoS ONE

EngineeringGeneticsDna AnalysisMolecular BiologyCfdna Urine Preserve +26

In vitro and in vivo investigations on the antitumour activity of Chelidonium majus

Rica Capistrano I., An Wouters, Filip Lardon, +3

Phytomedicine

BiochemistryAntiparasitic AgentMedicineVivo InvestigationsChelidonium Majus +8

Reducing Compounds Equivocally Influence Oxidation during Digestion of a High-Fat Beef Product, which Promotes Cytotoxicity in Colorectal Carcinoma Cell Lines

Thomas Van Hecke, An Wouters, Caroline Rombouts, +10

Journal of Agricultural and Food Chemistry

NutritionFood AnalysisPathologyVitro DigestionMeat Quality +18

Poly(I:C) primes primary human glioblastoma cells for an immune response invigorated by PD-L1 blockade

Jorrit De Waele, Elly Marcq, Jonas R.M. Van Audenaerde, +14

OncoImmunology