Kheem S. Bisht

SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress

Hyunseok Kim, Krish Patel, Kristi Muldoon‐Jacobs et al. · Cancer Cell · 2010 · 795 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +14

<i>SIRT3</i> interacts with the <i>daf-16</i> homolog <i>FOXO3a</i> in the Mitochondria, as well as increases <i>FOXO3a</i> Dependent Gene expression

Kristi Muldoon Jacobs, J. Daniel Pennington, Kheem S. Bisht et al. · International Journal of Biological Sciences · 2008 · 275 citations · Full text

Education, Genetics, Molecular Biology +11

Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity

Edward G. Mimnaugh, Wanping Xu, Michele D. Vos et al. · Molecular Cancer Therapeutics · 2004 · 211 citations · Full text

Medicine, Oncology, Pharmacology +15

Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach

David Gius, Hengmi Cui, C. Matthew Bradbury et al. · Cancer Cell · 2004 · 182 citations

Medicine, Cancer Biology, Oncology +17

Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity.

Kheem S. Bisht, C. Matthew Bradbury, David Mattson et al. · PubMed · 2003 · 178 citations

Medicine, Oncology, Pharmacology +10