Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress

Randa Tao, Mitchell C. Coleman, J. Daniel Pennington, +10

Molecular Cell

Reductive StressSignal TransductionSirt3-mediated DeacetylationRegulates Mnsod ActivityPhysiology +6

Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

Wenqiang Yu, David Gius, Patrick Onyango, +4

Nature

Epigenetic SilencingTumor BiologyAntisense RnaAntisense TherapyTumor Suppressor +5

SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress

Hyunseok Kim, Krish Patel, Kristi Muldoon‐Jacobs, +15

Cancer Cell

Reductive StressTumor BiologyMitophagyMitochondrial FunctionMedicine +5

Circadian Clock NAD ⁺ Cycle Drives Mitochondrial Oxidative Metabolism in Mice

Clara Bien Peek, Alison H. Affinati, Kathryn Moynihan Ramsey, +16

Science

Mitochondrial BiologyRedox BiologyOxidative StressBiosynthesisMitochondrial Oxidative Metabolism +20

SIRT2 Maintains Genome Integrity and Suppresses Tumorigenesis through Regulating APC/C Activity

Hyun‐Seok Kim, Athanassios Vassilopoulos, Rui-Hong Wang, +13

Cancer Cell

Suppresses TumorigenesisRegulating Apc/c ActivityCell RegulationMedicineTumor Suppressor +5

Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair

Shuang Zhang, Samuel E. Weinberg, Matthew DeBerge, +9

Cell Metabolism

InflammationBiochemistryBioenergeticsLipid PeroxidationPhysiology +11

Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3

Vinodkumar B. Pillai, Sadhana Samant, Nagalingam R. Sundaresan, +8

Nature Communications

Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation

Agnieszka A. Kendrick, Mahua Choudhury, Shaikh Mizanoor Rahman, +12

Biochemical Journal

Ionizing Radiation-Induced Oxidative Stress Alters miRNA Expression

Nicole L. Simone, Benjamin P. Soule, David Ly, +7

PLoS ONE

Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy

Pataje G.S. Prasanna, Deborah E. Citrin, Jeffrey Hildesheim, +29

JNCI Journal of the National Cancer Institute

Anti-agingAgingPathologyBiogerontologyCancer Biology +16