Hyun‐Seok Kim

Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice

Rui-Hong Wang, Kundan Sengupta, Cuiling Li et al. · Cancer Cell · 2008 · 773 citations · Full text

Chromatin, Genome Instability, Dna Damage +9

SIRT2 Maintains Genome Integrity and Suppresses Tumorigenesis through Regulating APC/C Activity

Hyun‐Seok Kim, Athanassios Vassilopoulos, Rui-Hong Wang et al. · Cancer Cell · 2011 · 528 citations · Full text

Suppresses Tumorigenesis, Regulating Apc/c Activity, Cell Regulation +7

Hepatic-Specific Disruption of SIRT6 in Mice Results in Fatty Liver Formation Due to Enhanced Glycolysis and Triglyceride Synthesis

Hyun‐Seok Kim, Cuiying Xiao, Rui-Hong Wang et al. · Cell Metabolism · 2010 · 505 citations

Metabolic Syndrome, Hepatology, Biochemistry +13

Interplay among BRCA1, SIRT1, and Survivin during BRCA1-Associated Tumorigenesis

Rui-Hong Wang, Zheng Yin, Hyun‐Seok Kim et al. · Molecular Cell · 2008 · 357 citations · Full text

Tumor Biology, Medicine, Brca1-associated Tumorigenesis +5

Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance

Rui-Hong Wang, Hyun‐Seok Kim, Cuiying Xiao et al. · Journal of Clinical Investigation · 2011 · 303 citations

Metabolic Disorder, Genetics, Immunology +23