C. Matthew Bradbury

Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach

David Gius, Hengmi Cui, C. Matthew Bradbury et al. · Cancer Cell · 2004 · 182 citations

Chromatin, Systems Biology, Multimodality Approach +13

Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity.

Kheem S. Bisht, C. Matthew Bradbury, David Mattson et al. · PubMed · 2003 · 178 citations

Heat Shock Protein, Tumor Biology, 17-Allylamino-17-demethoxygeldanamycin Potentiate +15

Epigenetic Silencing of Novel Tumor Suppressors in Malignant Melanoma

Viswanathan Muthusamy, Sekhar Duraisamy, C. Matthew Bradbury et al. · Cancer Research · 2006 · 168 citations · Full text

2-Deoxy-D-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism.

Xiao Juan Lin, Fanjie Zhang, C. Matthew Bradbury et al. · PubMed · 2003 · 150 citations

Radiation Effect, Radiation Exposure, Cell Death +22

Thioredoxin reductase regulates AP-1 activity as well as thioredoxin nuclear localization via active cysteines in response to ionizing radiation

Shervin Karimpour, Junyang Lou, Lilie L. Lin et al. · Oncogene · 2002 · 118 citations

Reductive Stress, Signal Transduction, Redox Regulator +11