Malini Ravi

Dual irreversible kinase inhibitors: Quinazoline-based inhibitors incorporating two independent reactive centers with each targeting different cysteine residues in the kinase domains of EGFR and VEGFR-2

Allan Wissner, Heidi L. Fraser, Charles L. Ingalls et al. · Bioorganic & Medicinal Chemistry · 2007 · 75 citations · Full text

Independent Reactive Centers, Drug Targeting, Medicine +8

Discovery of 4-(Benzylaminomethylene)isoquinoline-1,3-(2<i>H</i>,4<i>H</i>)-diones and 4-[(Pyridylmethyl)aminomethylene]isoquinoline-1,3-(2<i>H</i>,4<i>H</i>)-diones as Potent and Selective Inhibitors of the Cyclin-Dependent Kinase 4

Hwei‐Ru Tsou, Xiaoxiang Liu, Gary H. Birnberg et al. · Journal of Medicinal Chemistry · 2009 · 72 citations · Full text

Organic Chemistry, Selective Inhibitors, Heterocycle Chemistry +18

4D-QSAR Analysis of a Set of Ecdysteroids and a Comparison to CoMFA Modeling

Malini Ravi, A. J. Hopfinger, Robert E. Hormann et al. · Journal of Chemical Information and Computer Sciences · 2001 · 67 citations

Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment

Scott C. Mayer, A. Banker, Frank Boschelli et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 67 citations · Full text

Medicinal Chemistry, Medicine, Isoquinolinedione Inhibitors +9

4-(Phenylaminomethylene)isoquinoline-1,3(2<i>H</i>,4<i>H</i>)-diones as Potent and Selective Inhibitors of the Cyclin-Dependent Kinase 4 (CDK4)

Hwei‐Ru Tsou, Mercy Otteng, Tritin Tran et al. · Journal of Medicinal Chemistry · 2008 · 63 citations · Full text

Chemoprevention Strategy, Selective Inhibitors, Heterocycle Chemistry +16