Gary H. Birnberg

Discovery of 4-(Benzylaminomethylene)isoquinoline-1,3-(2<i>H</i>,4<i>H</i>)-diones and 4-[(Pyridylmethyl)aminomethylene]isoquinoline-1,3-(2<i>H</i>,4<i>H</i>)-diones as Potent and Selective Inhibitors of the Cyclin-Dependent Kinase 4

Hwei‐Ru Tsou, Xiaoxiang Liu, Gary H. Birnberg et al. · Journal of Medicinal Chemistry · 2009 · 72 citations · Full text

Organic Chemistry, Selective Inhibitors, Heterocycle Chemistry +18

4-(Phenylaminomethylene)isoquinoline-1,3(2<i>H</i>,4<i>H</i>)-diones as Potent and Selective Inhibitors of the Cyclin-Dependent Kinase 4 (CDK4)

Hwei‐Ru Tsou, Mercy Otteng, Tritin Tran et al. · Journal of Medicinal Chemistry · 2008 · 63 citations · Full text

Chemoprevention Strategy, Selective Inhibitors, Heterocycle Chemistry +16

Cheletropic .sigma.2s + .sigma.2s + .sigma.2s ejection of nitrogen from 9,10-diazasnoutenes as a route to monofunctionalized semibullvalenes. Ground state substituent effects on equilibrium displacements

D. R. James, Gary H. Birnberg, Leo A. Paquette · Journal of the American Chemical Society · 1974 · 50 citations

Chemical Kinetics, Engineering, Chemical Transformation +16

Synthesis and Biological Activity of Analogues of the Antimicrotubule Agent<i>N</i>,β,β-Trimethyl-<scp>l</scp>-phenylalanyl-<i>N</i>-[(1<i>S</i>,2<i>E</i>)-3-carboxy-1-isopropylbut-2-enyl]-<i>N</i>¹,3-dimethyl-<scp>l</scp>-valinamide (HTI-286)

Arie Zask, Gary H. Birnberg, Katherine Cheung et al. · Journal of Medicinal Chemistry · 2004 · 48 citations · Full text

Bioorganic Chemistry, Antiparasitic Agent, Novel Analogues +19

Discovery and optimization of 2-(4-substituted-pyrrolo[2,3-b]pyridin-3-yl)methylene-4-hydroxybenzofuran-3(2H)-ones as potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR)

Hwei‐Ru Tsou, Gloria MacEwan, Gary H. Birnberg et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 39 citations · Full text

Medicinal Chemistry, Mammalian Target, Biochemistry +11