Arie Zask

Biochemical, Cellular, and <i>In vivo</i> Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin

Ker Yu, Lourdes Toral‐Barza, Celine Shi et al. · Cancer Research · 2009 · 326 citations

Chemoprevention Strategy, Cellular Pharmacology, Selective Inhibitors +22

Multivalent Small-Molecule Pan-RAS Inhibitors

Matthew Welsch, Anna Kaplan, Jennifer M. Chambers et al. · Cell · 2017 · 273 citations · Full text

Medicinal Chemistry, Medicine, Pharmacotherapy +4

Beyond Rapalog Therapy: Preclinical Pharmacology and Antitumor Activity of WYE-125132, an ATP-Competitive and Specific Inhibitor of mTORC1 and mTORC2

Ker Yu, Celine Shi, Lourdes Toral‐Barza et al. · Cancer Research · 2010 · 208 citations · Full text

Antitumor Activity, Chemoprevention Strategy, Pharmacotherapy +22

HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.

Frank Loganzo, Carolyn Discafani, Tami Annable et al. · PubMed · 2003 · 137 citations

Microtubule Organization, Pharmacotherapy, Tripeptide Hemiasterlin +18

Synthesis of racemic frenolicin via organochromium and organopalladium intermediates

M. F. SEMMELHACK, Arie Zask · Journal of the American Chemical Society · 1983 · 122 citations

Molecular Sciences, Bioorganic Chemistry, Racemic Frenolicin +12