Gloria MacEwan

Acetylenic TACE inhibitors. Part 1. SAR of the acyclic sulfonamide hydroxamates

Jeremy I. Levin, J.M. Chen, Katherine Cheung et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 49 citations · Full text

Acyclic Sulfonamide Hydroxamates, Medicinal Chemistry, Pharmaceutical Science +11

Discovery and optimization of 2-(4-substituted-pyrrolo[2,3-b]pyridin-3-yl)methylene-4-hydroxybenzofuran-3(2H)-ones as potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR)

Hwei‐Ru Tsou, Gloria MacEwan, Gary H. Birnberg et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 39 citations · Full text

Medicinal Chemistry, Mammalian Target, Biochemistry +11

Synthesis and SAR of diazepine and thiazepine TACE and MMP inhibitors

Arie Zask, Joshua A. Kaplan, Xuemei Du et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 29 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Medicine +11

Benzodiazepine inhibitors of the MMPs and TACE. Part 2

Jeremy I. Levin, Frances C. Nelson, Efren Delos Santos et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 23 citations · Full text

Medicinal Chemistry, Medicine, Psychotropic Medication +5

4-Substituted-7-azaindoles bearing a ureidobenzofuranone moiety as potent and selective, ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR)

Hwei‐Ru Tsou, Gloria MacEwan, Gary H. Birnberg et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 20 citations · Full text

Medicinal Chemistry, Mammalian Target, Drug Target +12