Xuemei Du

Potent, selective, and orally bioavailable matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis

Yonghan Hu, Jason Xiang, Martin J. DiGrandi et al. · Bioorganic & Medicinal Chemistry · 2005 · 108 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9

Identification of potent and selective MMP-13 inhibitors

Junjun Wu, Thomas S. Rush, Rajeev Hotchandani et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 70 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Synthesis and SAR of highly selective MMP-13 inhibitors

Jianchang Li, Thomas S. Rush, Wěi Li et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 64 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +5

Characterization of (2R, 3S)-2-({[4-(2-butynyloxy)phenyl]sulfonyl}amino)-N,3-dihydroxybutanamide, a potent and selective inhibitor of TNF-α converting enzyme

Yuhua Zhang, Martin Hegen, Jun Xu et al. · International Immunopharmacology · 2004 · 55 citations

Life Sciences, Medicinal Chemistry, Pharmacology +11

Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment

Lori M. Miller, Scott C. Mayer, Dan M. Berger et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 42 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17