Jason Xiang

β-Keto sulfones as inhibitors of 11β-hydroxysteroid dehydrogenase type I and the mechanism of action

Jason Xiang, Manus Ipek, Vipin Suri et al. · Bioorganic & Medicinal Chemistry · 2007 · 113 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7

Potent, selective, and orally bioavailable matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis

Yonghan Hu, Jason Xiang, Martin J. DiGrandi et al. · Bioorganic & Medicinal Chemistry · 2005 · 108 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9

Stereospecific Alkenylation of C−H Bonds via Reaction with β-Heteroatom-Functionalized Trisubstituted Vinyl Triflones¹

Jason Xiang, Wanlong Jiang, Jianchun Gong et al. · Journal of the American Chemical Society · 1997 · 107 citations

Natural Sciences, Chemistry, Green Chemistry +13

Alkenylation of C−H Bonds via Reaction with Vinyl and Dienyl Triflones. Stereospecific Synthesis of Trisubstituted Vinyl Triflones via Organocopper Addition to Acetylenic Triflones¹

Jason Xiang, P. L. Fuchs · Journal of the American Chemical Society · 1996 · 95 citations

Natural Sciences, Chemistry, Catalysis +8

Synthesis and biological evaluation of sulfonamidooxazoles and β-keto sulfones: selective inhibitors of 11β-hydroxysteroid dehydrogenase type I

Jason Xiang, Manus Ipek, Vipin Suri et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 86 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8