Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo

David Borchelt, Gopal Thinakaran, Christopher B. Eckman, +17

Neuron

Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles

Neal G. Copeland, Debra J. Gilbert, Brian C. Cho, +6

Cell

Knockout MouseCytogeneticsSteel AllelesGeneticsChromosome Biology +7

The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells

Karen B. Avraham, Tama Hasson, Karen P. Steel, +5

Nature Genetics

Knockout MouseWaltzer Deafness GeneMolecular PhysiologyGeneticsUnconventional Myosin +11

Receptor tyrosine kinase specific for the skeletal muscle lineage: Expression in embryonic muscle, at the neuromuscular junction, and after injury

David M. Valenzuela, Trevor N. Stitt, Peter S. DiStefano, +15

Neuron

GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function

Paul A. Godfrey, Jason O. Rahal, Wesley G. Beamer, +3

Nature Genetics

Knockout MouseLittle MiceSignal TransductionMolecular PhysiologyAutoimmune Disease +12

Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias

Takuro Nakamura, David A. Largaespada, John D. Shaughnessy, +2

Nature Genetics

Hematological MalignancyCooperative ActivationMixed-phenotype Acute LeukemiaPbx1-related GenesHematology +6

A candidate mouse model for Prader–Willi syndrome which shows an absence of Snrpn expression

B.M. Cattanach, Jacqueline A. Barr, E.P. Evans, +7

Nature Genetics

Knockout MouseTranscriptional RegulationDevelopmental BiologyGenetic DisorderGenetics +5

The Cut-Homeodomain Transcriptional Activator HNF-6 Is Coexpressed with Its Target Gene HNF-3β in the Developing Murine Liver and Pancreas

Francisco M. Rausa, Uzma Samadani, Honggang Ye, +5

Developmental Biology

Target Gene Hnf-3βTranscriptional RegulationTranscription FactorsDevelopmental BiologySignal Transduction +11

Molecular genetic characterization of six recessive viable alleles of the mouse agouti locus.

Carolyn M. Hustad, William L. Perry, Linda D. Siracusa, +6

Genetics

Paracentric InversionGeneticsImmunologyMolecular GeneticsDisease Gene Identification +15

A Mouse Homolog of the Saccharomyces cerevisiae Meiotic Recombination DNA Transesterase Spo11p

Scott Keeney, Frédéric Baudat, Michael Angeles, +5

Genomics

Chromatin StructureMouse HomologNatural SciencesGeneticsMeiosis +6