GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function

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Gustavo González, Marc Montminy · Cell · 1989 · 2.5K citations

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CREB: a Ca ²⁺ -Regulated Transcription Factor Phosphorylated by Calmodulin-Dependent Kinases

Morgan Sheng, Margaret A. Thompson, Michael E. Greenberg · Science · 1991 · 1.5K citations

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Growth Hormone-Releasing Factor from a Human Pancreatic Tumor That Caused Acromegaly

Roger Guillemin, Paul Brazeau, Peter Böhlen et al. · Science · 1982 · 1.3K citations

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A G Protein-Linked Receptor for Parathyroid Hormone and Parathyroid Hormone-Related Peptide

Harald Jüppner, Abdul‐Badi Abou‐Samra, Mason W. Freeman et al. · Science · 1991 · 1.3K citations

Life Sciences, Biochemistry, Molecular Biology +17

Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1

Sen Li, E. Bryan Crenshaw, Elizabeth J. Rawson et al. · Nature · 1990 · 1.2K citations

Medicine, Genetics, Molecular Genetics +16