Tobias Gabriel - Concepedia

Author

Tobias Gabriel

Ludwig-Maximilians-Universität München

Also Known As

G. Tobias, Tobias Gabriel, Tobias S. Gabriel

Publications

1.1K

Citations

H-Index

Concepts

All Affiliations

Ludwig-Maximilians-Universität München Novartis (China)Roche (United States)Novartis (United States)

About

Tobias Gabriel is an author at Ludwig-Maximilians-Universität München specializing in drug discovery, natural sciences, and medicine.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	5	5	695
2	Natural Sciences	5	5	309
3	Biochemistry	5	5	317
4	Engineering	2	2	84
5	Biomolecular Engineering	2	2	94

Tobias Gabriel

Publications

943

Citations

H-Index

Page 1

	Year	Citations
Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1 Joseph Schoepfer, Wolfgang Jahnke, Giuliano Berellini, Journal of Medicinal Chemistry Drug TargetMixed-phenotype Acute LeukemiaMolecular BiologyTumor BiologyMyeloid Neoplasia	2018	432
Structure-Based Drug Design of RN486, a Potent and Selective Bruton’s Tyrosine Kinase (BTK) Inhibitor, for the Treatment of Rheumatoid Arthritis Yan Lou, Xiaochun Han, A. Kuglstatter, Journal of Medicinal Chemistry Pharmaceutical ScienceTyrosine KinaseImmunologySelective Btk InhibitorsPharmacotherapy	2014	106
Discovery of First-in-Class, Potent, and Orally Bioavailable Embryonic Ectoderm Development (EED) Inhibitor with Robust Anticancer Efficacy Ying Huang, Jeff Zhang, Zhengtian Yu, Journal of Medicinal Chemistry	2017	100
Discovery of 6-(2,4-Difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8<i>H</i>-pyrido[2,3-<i>d</i>]pyrimidin-7-one (Pamapimod) and 6-(2,4-Difluorophenoxy)-8-methyl-2-(tetrahydro-2<i>H</i>-pyran-4-ylamino)pyrido[2,3-<i>d</i>]pyrimidin-7(8<i>H</i>)-one (R1487) as Orally Bioavailable and Highly Selective Inhibitors of p38α Mitogen-Activated Protein Kinase David Goldstein, Michael Soth, Tobias Gabriel, Journal of Medicinal Chemistry PharmacotherapyNew SeriesSystem PharmacologyPharmaceutical ChemistryPre-clinical Pharmacology	2011	74
The chromium—Reformatsky reaction: Asymmetric synthesis of the aldol fragment of the cytotoxic epothilons from 3-(2-bromoacyl)-2-oxazolidinones Tobias Gabriel, Ludger A. Wessjohann Tetrahedron Letters Aldol FragmentBiochemistryAsymmetric SynthesisChromium—reformatsky ReactionPharmacology	1997	64
Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase Andreas Lingel, Martin Sendzik, Ying Huang, Journal of Medicinal Chemistry Histone ModificationsEed Binders AllostericallyEpigenetic ChangeMolecular BiologyEpigenetics	2016	56
Chromium(II)-Mediated Reformatsky Reactions of Carboxylic Esters with Aldehydes Ludger A. Wessjohann, Tobias Gabriel The Journal of Organic Chemistry EngineeringBiochemistryNatural SciencesChemical ReactionsAltmetric Attention Score	1997	46
The chromium-Reformatsky reaction: anti-selective Evans-type aldol reactions with excellent inverse induction at ambient temperature Tobias Gabriel, Ludger A. Wessjohann Tetrahedron Letters Excellent Inverse InductionCross-coupling ReactionEngineeringChromium-reformatsky ReactionOrganic Chemistry	1997	38
3-Amino-pyrazolo[3,4-d]pyrimidines as p38α kinase inhibitors: Design and development to a highly selective lead Michael Soth, Sarah C. Abbot, Allassan Abubakari, Bioorganic & Medicinal Chemistry Letters Molecular PharmacologyMedicinal ChemistryDrug TargetBiochemistryMedicine	2011	27

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