Giuliano Berellini

The allosteric inhibitor ABL001 enables dual targeting of BCR–ABL1

Andrew A. Wylie, Joseph Schoepfer, Wolfgang Jahnke et al. · Nature · 2017 · 596 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1

Joseph Schoepfer, Wolfgang Jahnke, Giuliano Berellini et al. · Journal of Medicinal Chemistry · 2018 · 447 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 1352 Drug Compounds

Franco Lombardo, Giuliano Berellini, R. Scott Obach · Drug Metabolism and Disposition · 2018 · 175 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +12

Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation

Cheryl Carson, Pichai Raman, Jennifer Tullai et al. · PLoS ONE · 2015 · 109 citations · Full text

Medicine, Oncology, Pharmacology +15

Comprehensive Assessment of Human Pharmacokinetic Prediction Based on In Vivo Animal Pharmacokinetic Data, Part 2: Clearance

Franco Lombardo, Nigel J. Waters, Upendra A. Argikar et al. · The Journal of Clinical Pharmacology · 2012 · 99 citations

Pharmacy, Pharmacokinetics, Pharmacology +16